4-Epianhydrotetracycline hydrochloride, 'can be used as a secondary standard'

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• 4-Epianhydrotetracycline hydrochloride is a secondary degradation product formed by epimerization of tetracycline and dehydration at the C6 position to aromatize the B ring
• It has 250-fold higher toxicity than either tetracycline or doxycycline depending on the system under study

Applications

• 4-Epianhydrotetracycline hydrochloride is less toxic to E. coli, and thus suitable for use with vectors or systems designed upon elements of the (Tn10) tet operon of E. coli
• This compound is also used in veterinary medicine research and as a secondary standard for application in quality control in pharmaceutical laboratories